Cheon Lab

Main Links

Logo and Main Menu

Full Menu

Research

Search

Total: 154 data, Page 6 of 16

104. [Precision Nanomedicine] Xinglu Huang, Fan Zhang, Yu Wang, Xiaolian Sun, Ki Young Choi, Dingbin Liu, Jin-sil Choi, Tae-Hyun Shin, Jinwoo Cheon, Gang Niu, and Xiaoyuan Chen*
Design Considerations of Iron-Based Nanoclusters for Noninvasive Tracking of Mesenchymal Stem Cell Homing
ACS Nano, 8(5), 4403-4414
 (Apr 22, 2014)

Stem-cell-based therapies have attracted considerable interest in regenerative medicine and oncological research. However, a major limitation of systemic delivery of stem cells is the low homing efficiency to the target site. Here, we report a serendipitous finding that various iron-based magnetic nanoparticles (MNPs) actively augment chemokine receptor CXCR4 expression of bone-marrow-derived mesenchymal stem cells (MSCs). On the basis of this observation, we designed an iron-based nanocluster that can effectively label MSCs, improve cell homing efficiency, and track the fate of the cells in vivo. Using this nanocluster, the labeled MSCs were accurately monitored by magnetic resonance imaging and improved the homing to both traumatic brain injury and glioblastoma models as compared to unlabeled MSCs. Our findings provide a simple and safe method for imaging and targeted delivery of stem cells and extend the potential applications of iron-based MNPs in regenerative medicine and oncology

103. [Precision Nanomedicine] Tae-Hyun Shin, Jin-sil Choi, Seokhwan Yun, Il-Sun Kim, Ho-Taek Song, Youngmee Kim, Kook In Park, and Jinwoo Cheon
"T1 and T2 Dual-Mode MRI Contrast Agent for Enhancing Accuracy by Engineered Nanomaterials"
ACS Nano, 8 (4), 3393-3401
 (Mar 27, 2014)

MRI contrast agent, nanoparticle, dual-mode contrast agent, stem cell tracking

102. [Precision Nanomedicine] Dongwon Yoo, Heeyeong Jeong, Seung-Hyun Noh, Jae-Hyun Lee, and Jinwoo Cheon
"Magnetically Triggered Dual Functional Nanoparticles for Resistance-Free Apoptotic Hyperthermia"
Angew. Chem. Int. Ed., 52 (49), 13047-13051
 (Dec 2, 2013)

Magnetic hyperthermia, drug release, drug-resistance, cancer, dual function

101. [Nanobio Interface] Mohammad Mehrmohammadi, Tae-Hyun Shin, Min Qu, Pieter Kruizinga,Ryan L. Truby, Jae-Hyun Lee, Jinwoo Cheon and Stanislav Y. Emelianov
"In vivo pulsed magneto-motive ultrasound imaging using high-performance magnetoactive contrast nanoagents"
Nanoscale, 5 (22), 11179-11186
 (Nov 21, 2013)

Magneto-motive ultrasound imaging, ultrasound, magnetoactive, contrast agent

100. [Nanobio Interface] Christine A. Falaschetti, Tatjana Paunesku, Jasmina Kurepa, Dhaval Nanavati, Stanley S. Chou, Mrinmoy De, MinHa Song,Jung-tak Jang, Aiguo Wu, Vinayak P. Dravid, Jinwoo Cheon, Jan Smalle, and Gayle E. Woloschak
"Negatively Charged Metal Oxide Nanoparticles Interact with the 20S Proteasome and Differentially Modulate Its Biologic Functional Effects"
ACS Nano, 7 (9), 7759-7772
 (Aug 9, 2013)

Iron oxide nanoparticle, TiO2, protein, ubiquitin-proteasome

99. [Precision Nanomedicine] Jae-Hyun Lee, Ji-wook Kim and Jinwoo Cheon
"Magnetic Nanoparticles for Multi-Imaging and Drug Delivery"
Mol. Cells, 35 (4), 274-284
 (Apr 30, 2013)

Magnetic drug delivery, magnetic hyperthermia, nanoparticle, magnetic resonance imaging, multi-mode imaging

98. [Precision Nanomedicine] Christian Preihs, Jonathan F. Arambula, Darren Magda, Heeyeong Jeong, Dongwon Yoo, Jinwoo Cheon, Zahid H. Siddik, and Jonathan L. Sessler*
"Recent Developments in Texaphyrin Chemistry and Drug Discovery"
Inorg. Chem., 52 (21), 12184-12192
 (Apr 4, 2013)

This article is part of the Metals in Medicine and Health special issue.

97. [Precision Nanomedicine] Jae-Hyun Lee, Kuan-Ju Chen, Seung-Hyun Noh, Mitch Andre Garcia, Hao Wang, Wei-Yu Lin, Heeyeong Jeong, Brian Junoh Kong, David B. Stout,Jinwoo Cheon, and Hsian-Rong Tseng
"On-Demand Drug Release System for In Vivo Cancer Treatment through Self-Assembled Magnetic Nanoparticles"
Angew. Chem. Int. Ed., 52 (16), 4384-4388
 (Mar 20, 2013)

Supramolecular, nanoparticle, thermal heating, drug release, cancer

96. [Evolutionary Nanomaterials & Nanodevices] Jae Hyo Han, Sujeong Lee, Dongwon Yoo, Jae-Hyun Lee, Sohee Jeong, Jin-Gyu Kim, and Jinwoo Cheon*
Unveiling Chemical Reactivity and Structural Transformation of Two-Dimensional Layered Nanocrystals
J. Am. Chem. Soc., 135 (10), 3736-3739
 (Mar 13, 2013)

2D-layered nanostructure, Lewis acid and base, TiO2, TiS2, transition metal chalcogenide

95. [Nanobio Interface] Dongwon Yoo, Heeyeong Jeong, Christian Preihs,Jin-sil Choi, Tae-Hyun Shin, Jonathan L. Sessler, and Jinwoo Cheon
"Double-Effector Nanoparticles: A Synergistic Approach to Apoptotic Hyperthermia"
Angew. Chem. Int. Ed., 51 (50), 12482-12485
 (Dec 7, 2012)

Hyperthermia, reactive oxygen species, cancer cell, nanoparticle, cell death, tumor

List

Copyright and Address

  • ADDRESS Department of Chemistry. 50 Yonsei-ro, Seodaemun-gu, Seoul 03722
  • TEL +82-2-2123-4748
  • FAX +82-2-2123-4640
  • EMAIL lee7626@yonsei.ac.kr
  • © Cheon Group | Yonsei University. All Right Reserved

Display Page Loading Image

Top