|[Precision Nanomedicine] Yoon Ho Roh†, Chang Yeol Lee†, Sujin Lee, Hyunho Kim, Amy Ly, Cesar M. Castro, Jinwoo Cheon, Jae-Hyun Lee*, and Hakho Lee* († equally contributed)
CRISPR-Enhanced Hydrogel Microparticles for Multiplexed Detection of Nucleic Acids
Adv. Sci., online published, 2206872 (Feb 1, 2023)
CRISPR/Cas systems offer a powerful sensing mechanism to transduce sequence-specific information int...
|[Precision Nanomedicine] Minsuk Kwak†, Kaden M. Southard†, Woon Ryoung Kim†, Annie Lin, Nam Hyeong Kim, Ramu Gopalappa, Hyun Jung Lee, Minji An, Seo Hyun Choi, Yunmin Jung, Kunwoo Noh, Justin Farlow, Anastasios Georgakopoulos, Nikolaos K. Robakis, Min K. Kang, Matthew L. Kutys, Daeha Seo, Hyongbum Henry Kim, Yong Ho Kim, Jinwoo Cheon, Zev J. Gartner*, and Young-wook Jun* († equally contributed)
Adherens Junctions Organize Size-Selective Proteolytic Hotspots Critical for Notch Signalling
Nat. Cell Biol., 24, 1739–1753 (Dec 1, 2022)
Adherens junctions (AJs) create spatially, chemically and mechanically discrete microdomains at cell...
|[Precision Nanomedicine] Wookjin Shin†, Sumin Jeong†, Jung-uk Lee, Soo Yeun Jeong, Jeonghong Shin, Hyongbum Henry Kim*, Jinwoo Cheon*, and Jae-Hyun Lee *(† equally contributed)
Magnetogenetics with Piezo1 Mechanosensitive Ion Channel for CRISPR Gene Editing
Nano Lett., 22 (18), 7415–7422 (Sep 7, 2022)
Regulation of genetic activity in single cells and tissues is pivotal to determine key cellular func...
|[Evolutionary Nanomaterials] Gwangmook Kim, Eoh Jin Kim, Hyung Wan Do, Min-Kyun Cho, Sungsoon Kim, Shinill Kang, Dohun Kim, Jinwoo Cheon, and Wooyoung Shim*
Binary-State Scanning Probe Microscopy for Parallel Imaging
Nat. Commun., 13, 1438 (Mar 17, 2022)
Scanning probe microscopy techniques, such as atomic force microscopy and scanning tunnelling micros...
|[Precision Nanomedicine] Hojeong Yu, Hoyeon Lee, Jiyong Cheong, Sang Won Woo, Juhyun Oh, Hyun-kyung Oh, Jae-Hyun Lee, Hui Zheng, Cesar M. Castro, Yeong-Eun Yoo, Min-Gon Kim, Jinwoo Cheon, Ralph Weissleder, and Hakho Lee*
A Rapid Assay Provides On-Site Quantification of Tetrahydrocannabinol in Oral Fluid
Sci. Transl. Med., 13 (616), 1-10 (Oct 20, 2021)
Tetrahydrocannabinol (THC), the primary psychoactive ingredient of cannabis, impairs cognitive and m...
|[Evolutionary Nanomaterials] Yongjun Lim, Seung-hyun Noh, Tae-Hyun Shin, Jung-uk Lee, Dominik Lungerich, Jae-Hyun Lee, and Jinwoo Cheon*
Magnetothermally Activated Nanometer-level Modular Functional Group Grafting of Nanoparticles
Nano Lett., 21 (8), 3649–3656 (Apr 15, 2021)
Nanoparticles with multifunctionality and high colloidal stability are essential for biomedical appl...
|[Precision Nanomedicine] Tae-Hyun Shin†, Pan Ki Kim†, Sunghwi Kang, Jiyong Cheong, Soojin Kim, Yongjun Lim, Wookjin Shin, Joon-Yong Jung, Jungsu D. Lah, Byoung Wook Choi*, and Jinwoo Cheon* († equally contributed)
High-Resolution T1 MRI via Renally Clearable Dextran Nanoparticles with an Iron Oxide Shell
Nat. Biomed. Eng., 5 (3), 252-263 (Mar 8, 2021)
Contrast agents for magnetic resonance imaging (MRI) improve anatomical visualizations. However, owi...
|[Precision Nanomedicine] Jung-uk Lee, Wookjin Shin, Yongjun Lim, Jungsil Kim, Woon Ryoung Kim, Heehun Kim, Jae-Hyun Lee, and Jinwoo Cheon*
Non-Contact Long-Range Magnetic Stimulation of Mechanosensitive Ion Channels in Freely Moving Animals
Nat. Mater., 20 (7), 1029–1036 (Jan 28, 2021)
Among physical stimulation modalities, magnetism has clear advantages, such as deep penetration and ...
|[Precision Nanomedicine] Jiyong Cheong†, Hojeong Yu†, Chang Yeol Lee, Jung-uk Lee, Hyun-jung Choi, Jae-Hyun Lee*, Hakho Lee*, and Jinwoo Cheon* († equally contributed)
Fast Detection of SARS-CoV-2 RNA via the Integration of Plasmonic Thermocycling and Fluorescence Detection in a Portable Device
Nat. Biomed. Eng., 4, 1159–1167 (Dec 3, 2020)
The diagnosis of severe acute respiratory syndrome 2 (SARS-CoV-2) infection by quantitative PCR with...
|[Nanobio Interface] Jiuk Jang†, Hyobeom Kim†, Sangyoon Ji, Ha Jun Kim, Min Soo Kang, Tae Soo Kim, Jong-eun Won, Jae-Hyun Lee, Jinwoo Cheon*, Kibum Kang*, Won Bin Im*, and Jang-Ung Park* († equally contributed)
Mechanoluminescent, Air-Dielectric MoS2 Transistors as Active-Matrix Pressure Sensors for Wide Detection Ranges from Footsteps to Cellular Motions
Nano Lett., 20 (1), 66-74 (Oct 22, 2019)
Tactile pressure sensors as flexible bioelectronic devices have been regarded as the key component f...